An increasing amount of cancer research is being directed towards the investigation of plant-derived anticancer compounds, many of which have been used in traditional herbal treatments for centuries.
Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anti-tumor and anti-leukaemic properties.
Following an overview of the disease and the diverse methods of therapy and clinical testing, the book provides a detailed examination of the plants whose compounds are currently used in conventional cancer treatment, the species which show the greatest potential as future candidates, and other species with established anticancer properties.
The third section explores each of more than terrestrial plant genera and species, with a review of their traditional uses, mythology, botany, active ingredients, and product applications, along with photographs and illustrations and an analysis of expected results and risks. The text closes with a discussion of algal extracts and isolated metabolites with anticancer activity, a summary of published research for each species, and chemical structures of the most important compounds.
Fasciolosis is a major global infection of livestock causing both huge losses to the agricultural community and affecting human health as a food-borne disease. Fully updated throughout, this new edition continues to cover the life cycle, biology, and development of the parasite; clinical pathology, immunology, diagnosis and vaccine development; and emergence, cause and mechanisms of drug resistance. It reviews the temperate liver fluke Fasciola hepatica, together with molecular, biochemical, control, and epidemiologial aspects of the tropical liver fluke F.
Many fundamental advances have taken place in the last two decades, but of particular importance has been the mapping of the draft genome of Fasciola. In addition, comprehensive advances in transcriptomics, proteomics and glycomics have been made, and the book therefore pays particular attention to these developments with the addition of brand-new chapters. Also covering the impact these parasites have had on the global human population, their distribution and their ecology, this book provides a comprehensive and accessible resource for scientists, researchers and students of medical and veterinary parasitology.
Glycobiology is an emerging field of studying glycans sugars and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology.
With technological advancements growing number of glycanns' functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research.
Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans.
The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics.
Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry. Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology.
Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events.
Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions. Discusses the sialic acids and their role in different diseases other than cancer Provides an understanding of sialylations as post translational modifications PTM Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health Gives insights on the importance of sialic acid biology through animal models.
Glycans at NCBI. Related information. Similar articles in PubMed. Macromolecular crowding: chemistry and physics meet biology Ascona, Switzerland, June Phys Biol. Epub Aug 2. Review Biological roles of glycans. Varki A. Epub Aug Implementation of GlycanBuilder to draw a wide variety of ambiguous glycans. Carbohydr Res. The third edition of this primary textbook in the field continues in the prior tradition, seeking to provide basic overview of Glycobiology, directed towards the advanced undergraduate or the beginning graduate-level student of molecular and cellular biology and biomedicine.
While efforts have been made to avoid a major increase in overall length of the text, substantial changes and improvements include the following: broader focus on all lineages of life forms in nature; wider range of topics, ranging from biology and medicine to chemistry and materials science; expanded international editorial board representing a wider range of expertise; wider range of contributing authors with expertise in specific areas; greatly expanded monosaccharide symbol nomenclature for the representation of glycans; and greater attention to informatics, and relevance to exploration of the glycome.
All rights reserved. Excerpt Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis, biology, and evolution of saccharides sugar chains or glycans that are widely distributed in nature in all living life forms. Monosaccharide Diversity: Chapter 2: Monosaccharide Diversity 3. Oligosaccharides and Polysaccharides: Chapter 3: Oligosaccharides and Polysaccharides 4. Glycosylation Precursors: Chapter 5: Glycosylation Precursors 6. Glycobiology is now one of the more rapidly growing fields in the natural sciences, with broad relevance.
Essentials of Glycobiology. Chemistry and Biochemistry of Food. This book provides an excellent platform for understanding the chemical processes involved in food transformation. Starting with the examination of major food components, such as water, carbohydrates, lipids, proteins and minerals, the author further introduces the biochemistry of digestion and energy metabolism of food ingredients. The last section of the. Anwendung finden Polysaccharide u.
Essential Biochemistry. Essential Biochemistry, 5th Edition is comprised of biology, pre-med and allied health topics and presents a broad, but not overwhelming, base of biochemical coverage that focuses on the chemistry behind the biology.
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